The Best St. Louis, MO Dog Rescues & Shelters in 2025

Stray Rescue of St. Louis

What sets Stray Rescue of St. Louis apart in the animal welfare community near and far? We seek out and take in those who no other organization will help or would simply euthanize because they are too expensive to heal. We take the abandoned, beaten, bred, fought, injured, terrified, defeated and betrayed. We see beyond their brokenness and are here to pick up the pieces to make these special animals whole again. We see the individual and know that there's no one size fits all treatment plan. The minute they enter our doors, we look in their eyes and promise them ALL the second chance they deserve for health, home, commitment and love. Because these animals come in with a story that would give us all nightmares, it takes them longer to open up, trust and believe in humankind again. But with patience and time always on their unique schedule we see the light shine in their eyes again. Animals have an amazing ability to forgive which never ceases to amaze us.

Unchained Melodies Dog Rescue

Unchained Melodies rescues, rehabilitates and rehomes chained, penned, and abused dogs that have no voice. We fight for stronger laws and have many programs that benefit our community.

Center for Animal Rescue & Enrichment of St. Louis - CARE STL

We accept the homeless, abused, neglected, injured, and surrendered animals of the City of St. Louis into our care so they will be safe and loved until they can be adopted into loving homes.

Needy Paws Rescue - St. Louis

Needy Paws Rescue is located in St. Louis, MO and exists through donations from the community. We are a 501(c)3 non-profit, volunteer, 100% foster-based organization saving dogs from high-kill shelters, strays, abandoned and surrendered in St. Louis and surrounding rural Missouri areas, regardless of breed or size.

Open Door Animal Sanctuary

The vision of Open Door Animal Sanctuary is to offer a loving environment and eventual home for every cat and dog in need of our help. We take in and adopt out nearly 1,400 dogs and cats per year! Open Door Animal Sanctuary is one of the area's largest no-kill animal shelters. Since our founding in 1975, we have provided hope, help and healing to tens of thousands of animals. We serve the community by taking in stray, homeless and otherwise unwanted cats and dogs. Each day, we provide shelter, food, medical care and most of all LOVE to 350 animals. Many of the precious angels who arrive at Open Door recognize for the first time in their lives that there can be love and trust in the world. Every animal that comes to us has a home and a second chance at life. We have a lifetime return policy which means if a family can no longer care for a cat or dog that was adopted from us, it must be returned to our sanctuary.

Great Pyrenees Rescue of Missouri

Great Pyrenees Rescue of Missouri is a nonprofit organization supported fully by volunteers and donations. Without the help of generosity - be it time, support or monetary - we would not be able to rescue the dogs that we do. We rescue, foster, and find new homes for dogs in Missouri and surrounding states - Illinois, Iowa, Kansas, Nebraska, Arkansas, and Oklahoma. our story Rescue has always been a passion of ours. Being able to help animals in need is one of the most rewarding ways to give meaning to life. We are dedicated to rescuing as many Great Pyrenees as we can, providing them with love, safety and a second chance at finding happiness with a forever home. In 2019, we started fundraising for a family that did not have the means to care for their sick Pyrenees and realized how much of a need there was for a Great Pyrenees Rescue in the Midwest. What started out with 2 rescue dogs and one foster family has quickly turned into over 350 successful adoptions, at at any given time about 15 foster families, and between 20-40 dogs in rescue awaiting their forever homes. If you would like to join our growing Great Pyrenees Rescue Team, please fill out a volunteer or foster application.

Serendipity German Shepherd Dog Rescue

Serendipity German Shepherd Dog Rescue is a state-licensed 501(c)3 non-profit rescue organization founded in 2004. Based in St. Louis, Missouri, we do our best to assist dogs in Missouri and surrounding areas.

Furever Shih Tzu & Companion Dog Rescue

Furever Shih Tzu Rescue is a nonprofit 501c organization that is dedicated to placing unwanted and abandoned purebred dogs into new homes. All donations are tax-deductible.

Pet Rescue Network

Pet Rescue Network, is a 501(c)(3) all volunteer organization licensed in the state of Missouri. It is comprised of dedicated and experienced volunteers determined to positively impact the lives of animals in need. We serve St. Louis and surrounding rural communities. Many PRN volunteers have 10 to 15 years experience in animal rescue activities. PRN strives to meet both the medical and psychological needs of animals who have suffered abuse, neglect, or abandonment through no fault of their own. What We Do Pet Rescue Network places unwanted and neglected pets in loving forever adoptive homes. While awaiting their permanent home, pets reside in loving foster homes and are treated as cherished family members. In order to secure the most permanent placements possible, PRN is committed to public education and thoughtful selection of potential families. Every rescued animal receives appropriate veterinarian care. PRN stresses the importance of spaying and neutering. We are strongly committed to promoting this throughout our community in an effort to reduce the number of unwanted pets. PRN participates in community outreach programs assisting citizens in finding low cost spay/neuter services when needed. PRN provides education to families regarding ways to provide structured, consistent, safe, and loving environments for all pets. We also provide education on the benefits of ongoing socialization and training for the family pet. By adopting from PRN, you can be assured that your new pet has been given the best of care. All animals reside in foster homes while awaiting adoption. They are socialized and assessed for behaviors, quirks and special needs PRIOR to being listed as “available” on our site. Since our adoptees are in homes, we usually know quite a bit about each pet’s individual personality. We can introduce each pet with information such as who does or does not interact well with other cats, dogs and children.

Franklin County Humane Society

FCHS is a privately run 501(c)(3) non-profit organization, tax ID 43-1244655, dedicated to serving the homeless, abandoned, and lost dogs and cats in our area. We incorporated in 1981 and operated as a foster network for homeless pets for 13 years. In 1994, we opened our current shelter location in Union, Missouri. FCHS is an open-admission animal shelter, which means we schedule intake of stray dogs and cats brought to us and provide them the opportunity of adoption into forever homes. We do not accept feral cats brought to our shelter in a trap. Feral cats are not adoptable as pets. We are the only open-admission animal shelter within a 40-mile radius. Each year we serve thousands of pets in Franklin County, Missouri and surrounding areas including: Augusta, Gerald, Hermann, Labadie, New Haven, Pacific, Robertsville, St. Albans, St. Clair, Sullivan, Owensville, Union, Washington and more. It costs over $1,800 a day to operate our shelter. We are supported by donations, fundraisers, grants and fees. We do not receive funding from Humane Society of Missouri, the United Way, federal, state or county governments or any animal welfare organizations.

Love A Golden Rescue

Love a Golden Rescue began in January 2001; at its foundation, it was a small group of volunteers who saw a need to help golden retrievers and golden retriever mixes in Central and Eastern Missouri and Central and Southern Illinois. That first year 50 dogs found forever homes. That was more than was anticipated, but we soon found that the "need" was larger than we initially thought. With everyone working together, the dogs received the necessary veterinary care, and lived in caring homes before moving into their forever homes. Adoption applications and home visits ensured that the forever families and the dogs were the right "fit." Now we are 22 years old, and have rescued more than 1400 dogs, all due to the concerted effort of our volunteers. Love a Golden has rescued dogs with a wide variety of needs. We have taken in pregnant dogs who delivered a litter soon after intake. We have saved goldens who required major surgery immediately after we took them in. We find great homes for golden retrievers who have spent all their lives in a breeding facility; they quickly become beloved family members. Seeing the photos from the new families---as the dogs snuggle on the couch with their two-legged and four-legged brothers and sisters or as they romp on the beach during a vacation--- is why rescue is so important to us. Not only do we strive to rescue goldens who have special needs but we also reach out to save seniors (dogs who are 9 years or older). Seniors have such a special place in Love a Golden's heart, and our Senior Life program recognizes the incredible families who adopt senior goldens. As foster homes are available we have taken labs, labs mixes and other dogs with no alternative.

The Feral Companion

We are a no-kill organization. Our group is very unique. We cater to all of those pups that take a long time to rehabilitate. In many shelters, there is no time for lengthy rehabilitation and sometimes workers lack experience with these shy dogs. We specialize in feral, shy, and special needs dogs. We want to help as many as we can that sometimes get overlooked in kill shelters. We assist the public, animal controls, other shelters and rescues with support for their feral dogs they want to work with.

Dogwood Farm Sanctuary

Dogwood Farm Sanctuary provides medical care, food, shelter and companionship to orphaned or abandoned animals, including horses, dogs, cats, and chickens. Although we find wonderful homes for many of our dogs and cats, some are deemed unadoptable because of age, temperament and/or special needs. For these animals, Dogwood Farm Sanctuary can offer a permanent sanctuary. Our Story Dogwood Farm Sanctuary became a 501c3 in 2005. However, we have been doing rescue for more than 30 years of dogs, cats and horses. We were formerly called Canine Rescue and funded by one individual. We decided to become a not-for-profit when a friend wanted to make a substantial donation on behalf of the animals. Since then, we continue to raise funds to help care for the animals at our facility. Most of the animals at our facility started as strays. We have many dogs and cats that would make excellent pets for a family: a family of one or a family of many. We work very hard to find appropriate homes for our dogs and cats. If an animal is deemed unadoptable, they will receive lifetime benefits of top veterinary care, a comfortable home at the facility and a premium diet. They also have daily human interaction and are carefully monitored. Our goal is to emulate a home environment for our dogs and cats and provide the best care within a small farm environment for our chickens and horses.

St. Louis Samoyed Rescue

Warrenton Animal Control Shelter

Dirk's Fund

History of Dirk’s Fund Our story begins in the 1980s, when the founder and his wife started rescuing dogs. Through the popularity of their own Golden Retrievers, Sadie and Hannah, they were contacted by animal control regarding a Golden Retriever that was going to be euthanized. Her name was Jenny. They were able to find her a home and then replaced her with another homeless dog. This is the cycle that started Dirk’s Fund. They rescued rehabilitated and found loving homes for eleven dogs in the first year. The director and his wife used their own home, resources and personal time to make sure each and every dog’s life had a happy ending.

Is Today My Day Rescue

Is Today My Day Rescue (ITMD) was formed by a group of dog-loving individuals in July of 2017. ITMD is a licenced, 501c3, non-profit dog rescue that strives to help homeless dogs find permanent placement in adoptive homes. We are a foster-based rescue with most of our fosters within an hour of St. Louis, MO. Our primary service area is rural south central Missouri. After two major animal shelters/rescues in the area permanently shut their doors, resources for dogs in need in this area were few and far between. It is an area with significant canine overpopulation and few resources. We work with individuals from this area to rehome personal dogs and help place stray dogs. Our community outreach includes altering family pets to reduce the overall dog population in the area as well as providing preventative care and dog food for families in need. While our focus is rural south central Missouri, we will help any dog we can. Our dogs come from a variety of circumstances, including strays, owner relinquishes, breeder releases, animal control facilities, and dogs at risk of euthanasia.

Country Acres Rescue

Founded in 2000, Country Acres Rescue is a 501(c)(3) non-profit, St. Louis based organization whose primary concern lies with the over population and unnecessary suffering of domestic animals in our community. We are dedicated to the rescue, rehabilitation, socialization and placement of homeless, abandoned and abused/neglected cats, dogs, kittens, and puppies.

Stray Paws Rescue

Stray Paws Rescue is a 501c3 nonprofit, foster based rescue. Our organization believes it is our moral responsibility to protect and improve the lives of rescued animals and place them in loving permanent homes in St. Louis Metro Area.

Saint Louis Scottish Terrier Rescue

St. Louis Scottish Terrier Rescue is dedicated to the rescuing, vetting & re-homing of purebred Scottish Terriers. Our adoptable Scotties come from animal shelters, commercial breeders, and owner releases. We completely vet every dog to the best of our abilities. Each dog is spayed/neutered, tested for heartworms and given all applicable vaccinations. A Scottie in our rescue lives in a foster home where he will receive one on one attention and evaluation along with a lot of love. Scotties ready for adoption can be found via the Available Dogs button above.

Five Acres Animal Shelter

Five Acres believes in the power of pets and seeks to enrich the lives of pets and their owners. Our values include:  Community – Five Acres exists to serve its community. This includes not only reducing the number of pets in need by finding them homes, but also supporting the pet owners in our community.  Lasting Relationships – Whether you adopt, foster, volunteer, donate, attend an event, or spread the word about our mission, you are a part of the Five Acres Family! We love creating relationships with our community, and we especially love to witness the new and strengthening bonds between humans and their pets.  Safe & Thriving Environments for our Animals – The safety and well-being of our animals is of the highest importance to our organization. We want the spaces in which our animals live to not just be safe and clean, but enriching and relaxing as well. Providing this for our animals is the top priority of our team.  Enriching the Lives of Pets & People – We believe that pets are better off with people, and people are better off with pets! Everything we do is to improve and foster the connection between humans and animals, but it doesn’t end with just adoption. It includes a robust foster program, impactful volunteer opportunities, community events, our AniMeals Food Pantry, and so much more. In 2022 our values led Five Acres Animal Shelter to the strategic decision to move toward the Human Animal Support Services model (often referred to as HASS), focused on not only finding homes for pets in need in our community, but also promoting a lasting and healthy relationship between pets and their owners. Our History Five Acres Animal Shelter formed in 1973 as the St. Charles County Humane Society, by a small group of individuals dedicated to animal welfare. Five Acres utilized volunteer foster homes for animals in need of adoption until the first shelter opened in 1988. In 1996, Five Acres acquired the current property on Pralle, operating the only no-kill feline house and canine shelter in St. Charles County. We added the Ruth Anne Scheidegger Canine Adoption Building in 2012, and the Kathryn Favre Kitty Cottage was completed in 2016. Five Acres remains free and clear of debt, and in 2021, we took in 1,691 animals. We adopted out 1,435 and reunited 270 animals with their families in that same year.

St. Louis Senior Dog Project

The St. Louis Senior Dog Project is a foster-based dog rescue organization specializing in older dogs but also taking and finding homes for dogs of all ages.

Stepping Stone Bully Rescue

All About Paws

Nonprofit Providing a Safe Haven for Animals All About Paws is a 501c3 group of volunteer animal lovers whose mission is to rescue, provide sanctuary, and ultimately re-home abandoned, stray, and neglected companion animals. All animals in our care are spayed or neutered and receive the necessary medical attention. The All About Paws foster home system provides a safe haven for the animals until they can be placed in carefully screened forever homes.

Even Chance Pitbull Rescue

Hootie's Rescue Haven

Hootie’s Rescue Haven is a not for profit no kill animal shelter. We care for unwanted and seriously ill pets. Our goal is to rehabilitate and adopt out the animals we take in to our shelter. We will leave a solid foundation for this rescue to be built on by future generations. With your support we placed 38 dogs and 10 cats in loving homes in 2019. We provide emergency medical care, medication and food supplies to animals in need.

PALS Animal Shelter

PALS is essentially a “no-kill” shelter. The only time an animal is euthanized is if it is too sick to be treated or too aggressive to be suitable for adoption. Even in these circumstances, the decision to euthanize is not taken lightly and must be approved by our Board of Directors. Other than for those reasons, a pet will have a caring home with PALS until adopted.

Jefferson County Animal Control

The Animal Control Division is committed to the enhancement of responsible pet ownership for all animals. We respond to requests for service regarding dogs and cats running at large, animal neglect and abuse, injured animals and wild animals inside the living areas of a home. Roles We investigate neglect and abuse allegations, investigate and quarantine animals for potential rabies exposure, while also providing adoption services in our shelter. We inspect and license dog and cat boarding and breeding facilities, as well as animal rescue facilities and foster-care homes. We maintain a "lost and found" canine and feline list of animals reported to us. We also operate the Animal Resource Center as a rabies quarantine facility and temporary housing facility for dogs and cats available for rescue and adoption. Enforcement The Animal Control Division enforces Chapter 215: Animal Control Order to protect public health and safety. Awards Jefferson County Animal Control has been awarded the No-Kill award from the Best Friends Animal Society for 2022 and 2023 due to having a live release rate of 90% or greater. This means that animals are only euthanized if medically necessary or due to severe behavioral issues. Jefferson County Animal Control is proud to say that we have not euthanized an adoptable animal in over seven years.

Missouri K9 Friends

Missouri K9 Friends is a 501(c)3 non-profit volunteer led organization. We rescue dogs in need, advocate for animal welfare, and promote ending breed discrimination

Midwest Doberman Rescue of St. Louis

Midwest Doberman Rescue of St. Louis is a not-for-profit (501(c)3) operating under Purebred Dog Rescue of S t. Louis, an all volunteer organization. We do not have a shelter or kennels, rather we take dogs into "foster care". Our first priority are the Dobermans who are in pounds, shelters or humane societies who have no other options and will be euthanized if we don't take them. Our second priority is helping people who have inherited a dog from a relative who has passed away or who because of circumstances beyond their control are no longer able to care for their Dobermans. Our last priority are owner surrenders. Our preference is to help you place your own dog. We will list your dog on our web site and prescreen all applicants prior to giving them your phone number. The transition from your home to a new home will be easier on the dog if they don't have to go into foster care first. We want every Doberman to be able to live out his/her natural life in a loving home. We want every adoption to be a happy, permanent placement. Each Doberman available for adoption is screened as carefully as possible. The simple fact is that not all dogs are appropriate for certain environments. Some dogs have specific temperaments and needs that not everyone can provide. You are asked to fill out an application before you meet our Dobermans so we can fit the right dog with your family.